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Medical research library
Research tools and study planning
Find original evidence, compare discovery platforms, and prepare a study other researchers can review.
Start with a study brief
Write down the question, sources, outcomes, and analysis plan. Use the brief for an evidence review, a secondary-data study, or a proposal for new research.
Find a tool for your next step
Find papers, trials, and reviewsSearch the literature and compare trial records across registries.
- Europe PMC
Search biomedical papers, citations, and links to full text. API guide
- Clinical trial registry
Search ClinicalTrials.gov records by condition or registration number and filter for posted results. Source API documentation
- WHO trial registry search
Search records from multiple national and regional trial registries.
- Cochrane Handbook
Plan a systematic review and assess risk of bias and certainty of evidence.
Investigate drug and target hypothesesCompare target evidence, measured bioactivity, and repurposing signals.
- Open Targets Platform
Compare evidence linking a target to a disease. GraphQL API
- ChEMBL
Look up measured bioactivity, assays, and compound records. Web services guide
- Broad Drug Repurposing Hub
Browse annotated medicines and research compounds, with links to related profiling projects.
- NCATS Biomedical Data Translator
Explore a research system that connects biomedical data sources to help form hypotheses.
- FDA–NIH CURE ID
Find reports of novel uses of existing drugs. Use case reports to formulate questions for further study.
- Every Cure MATRIX
See how a funded program plans to prioritize repurposing candidates and validate them. This link opens the program overview.
Find research dataCheck the access conditions and permitted uses for the dataset you choose.
- NCBI Gene Expression Omnibus
Find public functional genomics studies and their deposited data.
- PhysioNet
Find physiologic and clinical datasets. Access may be open, restricted, or credentialed.
- Vivli
Browse available clinical studies and request participant-level data with a research proposal.
Register, report, and review a studyMake the original plan and any changes visible to reviewers.
- Open Science Framework
Create a time-stamped registration of a study plan when appropriate.
- EQUATOR Network
Choose a reporting checklist that matches your study design.
- Cochrane peer review guidance
See how one review program handles reviewer selection, conflicts, and public involvement.
See how other institutes support researchExamples of investigator support, public portfolios, governed access, and patient involvement.
- Mayo Clinic CCaTS
See how an institute connects investigators to design, statistics, informatics, and ethics consults.
- European Clinical Research Infrastructure Network
Explore a public portfolio that shows what a clinical research network is working on.
- Wellcome Sanger Institute
See the application and review process for controlled research datasets.
- Australian Clinical Trials Alliance
Plan how patients and community members can contribute to research decisions.
External resources are maintained by their respective organizations. Review their access terms and cite the underlying records used in your study.